Dear Mr./Ms.,
Sanyou Biopharmaceuticals focuses on providing integrated solution for therapeutic antibody discovery and development, and offers all sorts of services for therapeutic antibody R&D.
In terms of anti-LAG3/MHC-II in vitro efficacy evaluation, we developed luciferase-reporter-based efficacy evaluation system, including engineered Jurkat monoclonal cell line overexpressing human LAG-3 and NF-AT-Luc2 as effector cells, and Raji as the APC. This luciferase-reporter-based method has better reproducibility, precision and linearity, comparing to the conventional method using primary cells as effector cells. Thus, it would be your perfect choice for the efficacy evaluation of anti-LAG3/MHC-II therapies.
ADVANTAGES
1) Reliable：No primary cells, more reliable than conventional method.
2) Sensitive：ng-level sensitivit.
3) Extreme Cost-performance：Only 1,548 USD per sample.
Make your efficacy evaluation easier!
Service
| Service |
Input |
Time |
Output |
Price |
| Efficacy Evaluation |
Test samples &
reference samples
|
2 weeks |
Reports |
$ 1,548
per sample
|
| Luciferase Reporter Cell Line |
N.A.
|
1 weeks |
Cell line |
$ 7,500
|
Note: If cells are not cultured, it would take another week for preparation.
EXAMPLE
| LAG3-NF-AT-Jurkat were mixed with superantigen SED pre-loaded Raji cell. After an 18-hr incubation with anti-LAG3 mAb, relatimab, the luminescence intensity was detected, and the result was showed on the left. The LAG3/MHC-II signal pathway could be in-activated by relatimab in a dose dependent manner (Learn more). |
|
|
OTHERS
PD-1/PD-L1 | CD40/CD40L | TIGIT/PVR | IL-33/ST-2 | VEGF/VEGFR2 | Learn more.
Do you need assistance with efficacy evaluation?
ABOUT US
Sanyou Biopharmaceuticals is a leading international High-tech biotechnology company focused on research, development and providing integrated solutions for innovative antibody drug developments.
Sanyou Bio is committed to building world-leading antibody drug discovery and development platforms of high-quality, high-throughput, integrated R&D and value transformation. Sanyou Bio is dedicated in constructing a business ecosystem for therapeutic, R&D and diagnostic products and services, and collaborating with global biopharmaceutical, diagnostic, R&D companies to open a new era for the diagnosis and treatment of human diseases.
Since the founding in the year of 2015, Sanyou Bio has been growing rapidly. As of May 2021, Sanyou Bio has a professional team of more than 160 employees, of which more than 70% hold a PhD or master degree, and this team is deeply experienced in R&D and industrialization of innovative drugs. Sanyou Bio has established an integrated R&D laboratory of several thousands of square meters with advanced facilities in Caohejing Hi-Tech Park in Shanghai. The laboratory have 10 functional modules and more than 40 core technology platforms, led by a series of super-trillion phage display antibody libraries, and followed by a full range of essential R&D platforms for innovative antibody drug discovery, antibody engineering, in vitro and in vivo efficacy screening, pharmaceutical properties analysis, cell line construction, and process development. Sanyou Bio continues to provide new technologies, new products, services and solutions of "best quality, fastest speed and lowest cost". Sanyou Bio has established friendly business relationships with more than 100 pharmaceutical companies, drug development organizations and diagnostic product development companies around the world.
"Excellence and innovation, pursuit of dreams, striving and evolving, for the benefit of patients", holding these principles and beliefs, Sanyou Bio looks forward to working with our customers and partners to build a long-term synergistic growth ecosystem and a healthy society.
You're welcome to send an email and tell us what's your need, and we will get back to you ASAP.
Sincerely.
Qingyang
Customer Specialist
Sanyou Biopharmaceuticals Co., Ltd.
Address: Building 6, No.188 Xinjunhuan Road,
Minhang District, Shanghai, China 201114
Email: service@sanyoubio.com
Tel: +86-21-3368 1627
Website: www.sanyoubio.com
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